Anticancer therapeutic efficacy of biogenic Am-ZnO nanoparticles on 2D and 3D tumor models

ZnO Nanoparticles: A Promising Anticancer Agent

Nanoparticles, with their selective targeting capabilities and superior efficacy, are becoming increasingly important in modern cancer therapy and starting to overshadow traditional cancer therapies such as chemotherapy, radia‐ tion and surgery. ZnO nanoparticles, with their unique properties such as biocompatibility, high selectivity, enhanced cytotoxicity and easy synthesis, may be a promisin...

Novel biogenic synthesis of silver nanoparticles and their therapeutic potential.

Here, we explored the medicinal uses of the novel biogenic silver nanoparticles of Pterospermum acerifolium (PaAgNPs) as a cost effective, eco-friendly, reducing and stabilizing compounds. The formation of PaAgNPs was confirmed by changing its color from colorless to yellowish brown, with maximum absorbance at 417 nm. FTIR spectrum of PaAgNPs suggested the presence of polycyclic compound simila...

Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery

Two-dimensional (2D) cell cultures growing on plastic do not recapitulate the three dimensional (3D) architecture and complexity of human tumors. More representative models are required for drug discovery and validation. Here, 2D culture and 3D mono- and stromal co-culture models of increasing complexity have been established and cross-comparisons made using three standard cell carcinoma lines:...

Skewed 2D Hilbert Transforms and Computed AM-FM Models

Biogenic Synthesis of Silver Nanoparticles Using Mustard and Its Characterization

The field of nanobiotechnology mainly encompasses with physics, biology, chemistry and material sciences and it develops novel therapeutic nano-scale materials for biomedical, drug delivery, cancer therapy and pharmaceutical applications. Silver nanoparticles (AgNPs) have unique physiochemical, biological and environmental properties which make them useful in a wide range of applications, s...